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Tangential Flow Filtration Methods and Benefits

Posted by BPES on Nov 19, 2019, 1:16:07 PM

Methods and Benefits of TFF In DownStream Process Filtration

Various methods and systems are available for the separation of cells from culture media in downstream bioprocessing. The most common include filtration, flotation, flocculation, and centrifugation (1). 

Filtration is perhaps the most popular technique for separating contaminants from process fluids.

During process filtration, different flow-through mechanisms can be used with an assortment of membrane media differentiated by porosity, or molecular weight.  

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Topics: bioprocessing equipment, tangential flow filtration

Bioprocessing Equipment Takes Many Forms

Posted by Luke Ciarfella on Aug 24, 2017, 3:45:37 PM

Upstream, Downstream, and Everything Between

Broadly defined, bioprocessing is a form of high-purity manufacture which employs living cells to engineer commercially viable productsIn addition to agriculture, fuel, chemical, and environmental sectors, the biopharmaceutical industry is one of the biggest users and beneficiaries of this process. 

Across all applications, bioprocessing requires specialized equipment ranging from bioreactor vessels, to filtration devices, mixers and all related piping, stands/holders, and transfer components. 

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Topics: bioprocessing equipment

Custom Fabricated Clean Room Carts

Posted by Luke Ciarfella on Jul 31, 2017, 8:27:03 AM

Attention To Detail

Here at BPES, we understand that every biopharmaceutical facility is unique in its size, shape, design, equipment and process.

In order to meet the often diverse storage and transfer needs of highly specialized high-purity manufacturing spaces, custom clean room carts and tables are a must. 

Clean room carts and tables carry specialty tools, bioprocessing equipment, chemicals, biological samples, computers and more. Therefore, the quality and design of their construction is critical for personnel safety, equipment safety, and maintaining clean room standards.

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Topics: Clean Room Standards, BPES, Custom Clean Room Carts, bioprocessing equipment

Custom Planova Filter Stands:  A Superior Single-Use Solution

Posted by Luke Ciarfella on Jun 16, 2017, 8:31:46 AM

Custom Planova Filter Stands Increase Drug Production Efficiency and Reduce Contamination Risk

The advent and rapid commercialization of new biological molecules such as monoclonal antibodies, vaccines, recombinant proteins and blood derivatives has led to a radically re-imagined pharmaceuticals manufacturing environment

Drug-makers are now being challenged to quickly produce pilot batches of new protein based medicines and rapidly scale these to production quantities.

The movement away from large “blockbuster” drugs to smaller batch drugs that are targeting a smaller population has led to the development of facilities that can produce multiple products flexibly and scalably while still meeting GMP (good manufacturing practices).

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Topics: biopharmaceutical manufacturing, virus filtration, custom planova filter stands, BPES

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