The unique configuration of the BPES high performance single‐pass tangential flow filtration holder allows the retentate from the first bank of filter modules to be fed directly into the feed port of the 2nd bank of filter modules. This can be repeated from 2 up to 4x. This allows up to a 4X concentration of product with one single pump pass.
The BPES Standard Tangential Flow Filtration cart with BPES universal TFF holder offers the perfect combination of quality, flexibility and value. The holder is directly compatible with MilliporeSigma and Pall UF Cassettes. Sartorius and others can be loaded with optional adapter plates.
CIP (Cleaning‐In‐Place) and SIP (Sterilization‐In‐Place) are the best methods for cleaning process systems. They ensure safety and efficiency, prevent toxic contamination of products and minimize possible contamination of the process. Well‐designed SIP / CIP systems provide for automatic cleaning and disinfecting without major disassembly and assembly and permit cleaning of one part of the plant while other areas continue to produce product.
Topics: bioprocessing equipment, clean in place, tangential flow filtration
Various methods and systems are available for the separation of cells from culture media in downstream bioprocessing. The most common include filtration, flotation, flocculation, and centrifugation (1).
Filtration is perhaps the most popular technique for separating contaminants from process fluids.
During process filtration, different flow-through mechanisms can be used with an assortment of membrane media differentiated by porosity, or molecular weight.