Our Process Control Interface (PCI) is a highly flexible, open source automation system that comes available on all BPES process skids. Our user-friendly standard software configuration enables automated process control and easy integration with other systems and entire process facilities.
Topics: bioprocessing equipment
Biopharm Engineered Systems is pleased to announce the development of an ultra-high accuracy, wide concentration bandwidth, Inline Buffer Dilution System (IDS) to support the manufacture of Monoclonal Antibodies (MAb's) and mRNA Therapeutics. The IDS was designed with the capability of tempering bulk caustic (8N NaOH) from an exterior supply, and diluting the tempered solution to 5N, 0.5N and 0.1N solutions for Process and Clean-In-Place (CIP) operations.
Topics: bioprocessing equipment
The unique configuration of the BPES high performance single‐pass tangential flow filtration holder allows the retentate from the first bank of filter modules to be fed directly into the feed port of the 2nd bank of filter modules. This can be repeated from 2 up to 4x. This allows up to a 4X concentration of product with one single pump pass.
The BPES Standard Tangential Flow Filtration cart with BPES universal TFF holder offers the perfect combination of quality, flexibility and value. The holder is directly compatible with MilliporeSigma and Pall UF Cassettes. Sartorius and others can be loaded with optional adapter plates.
CIP (Cleaning‐In‐Place) and SIP (Sterilization‐In‐Place) are the best methods for cleaning process systems. They ensure safety and efficiency, prevent toxic contamination of products and minimize possible contamination of the process. Well‐designed SIP / CIP systems provide for automatic cleaning and disinfecting without major disassembly and assembly and permit cleaning of one part of the plant while other areas continue to produce product.
Topics: bioprocessing equipment, clean in place, tangential flow filtration
Various methods and systems are available for the separation of cells from culture media in downstream bioprocessing. The most common include filtration, flotation, flocculation, and centrifugation (1).
Filtration is perhaps the most popular technique for separating contaminants from process fluids.
During process filtration, different flow-through mechanisms can be used with an assortment of membrane media differentiated by porosity, or molecular weight.
Broadly defined, bioprocessing is a form of high-purity manufacture which employs living cells to engineer commercially viable products. In addition to agriculture, fuel, chemical, and environmental sectors, the biopharmaceutical industry is one of the biggest users and beneficiaries of this process.
Across all applications, bioprocessing requires specialized equipment ranging from bioreactor vessels, to filtration devices, mixers and all related piping, stands/holders, and transfer components.
Topics: bioprocessing equipment
Here at BPES, we understand that every biopharmaceutical facility is unique in its size, shape, design, equipment and process.
In order to meet the often diverse storage and transfer needs of highly specialized high-purity manufacturing spaces, custom clean room carts and tables are a must.
Clean room carts and tables carry specialty tools, bioprocessing equipment, chemicals, biological samples, computers and more. Therefore, the quality and design of their construction is critical for personnel safety, equipment safety, and maintaining clean room standards.
Topics: bioprocessing equipment